Polímeros: Ciência e Tecnologia
https://www.revistapolimeros.org.br/doi/10.1590/0104-1428.0343?lang=en
Polímeros: Ciência e Tecnologia
Scientific & Technical Article

Microencapsulação do pesticida cipermetrina em blendas de P(3HB/PCL): caracterização e ensaio de liberação in vitro

Microencapsulation of cypermethrin pesticide in P(3HB)/PCL blends: characterization and in vitro controlled release

Dall’Agnol, Evana Cássia; Suave, Jaqueline; Meier, Marcia Margarete; Soldi, Valdir; Silva, Denise Abatti Kasper; Pezzin, Ana Paula Testa

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Resumo

A aplicação de polímeros biodegradáveis para encapsular pesticidas é uma estratégia que permite, a partir de diferentes proporções entre os polímeros, modificar o perfil de liberação do agente. Este trabalho avaliou a liberação controlada do pesticida cipermetrina encapsulado em microesferas de blendas de P(3HB)/PCL (100/0, 0/100, 97/03, 95/05, 90/10, 80/20 e 70/30) obtidas pelo método de emulsificação-evaporação do solvente. As imagens de microscopia eletrônica de varredura revelam a forte influência da PCL na porosidade das microesferas. As análises de infravermelho mostraram a presença do pesticida em todas as composições de polímeros avaliadas. O ensaio de liberação de cipermetrina sugere que, no intervalo de 4 horas, o teor de cipermetrina liberada é dependente da composição das blendas utilizadas. As microesferas de PHB e blendas com menores teores de PCL, 97/03 e 95/05 liberaram 75% a 85% enquanto a composição 70/30 liberou 100% de cipermetrina.

Palavras-chave

polímeros biodegradáveis, blendas, microencapsulação.

Abstract

This work evaluated the controlled release of cypermethrin pesticide loaded in microspheres of P(3HB)/PCL blends obtained by emulsion-evaporation method. SEM analysis revealed a strong influence of PCL on the porosity of the microspheres. The infrared spectra showed the presence of pesticide in all polymer compositon evaluated. DSC curves showed that with higher content of PCL, decreased the crystallinity degree of polymers, resulting in a faster release of the pesticide. The release assay of cypermethrin suggests that within an interval of four hours the amount of pesticide released varies depending on the composition of the blends.

Keywords

biodegradable polymers, blends, microencapsulation.

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